Basic pharmacology of local anaesthetics
نویسندگان
چکیده
منابع مشابه
PHARMACOLOGICAL STUDIES ON NOVEL BASIC AMINOALKYL ARYL ETHERS AS POTENTIAL LOCAL ANAESTHETICS
Following our previous investigations on certain new aminoalkyl aryl ethers, which showed promising and outstanding local anaesthetic properties, the local anaesthetic activity and duration of action of a further selection of four novel derivatives of the above-mentioned series, used as hydrochloride salts, have been determined by the ill vivo rat sciatic nerve test. These are: N,N-dimethyl...
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Introduction The science of pharmacology is concerned with the effects of drugs on the function of living tissues (Greek: Pharmakos = drug, Logos = study). Since modern medicine relies heavily on drugs as the principal tool for the treatment and prevention of disease, it is important that all clinicians possess a basic understanding of the pharmacological principles that govern their clinical u...
متن کاملpharmacological studies on novel basic aminoalkyl aryl ethers as potential local anaesthetics
following our previous investigations on certain new aminoalkyl aryl ethers, which showed promising and outstanding local anaesthetic properties, the local anaesthetic activity and duration of action of a further selection of four novel derivatives of the above-mentioned series, used as hydrochloride salts, have been determined by the ill vivo rat sciatic nerve test. these are: n,n-dimethyl-2-(...
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AIM To compare the effectiveness of EMLA cream and Ametop gel in providing analgesia for venous cannulation. METHODS Single blind study in 120 children. RESULTS Both anaesthetic agents produced adequate analgesia. However, Ametop gel was more effective, with a statistically significant difference in the pain scores of the two groups (p < 0.05).
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and Md., Eight synthetic local anaesthetics from among (he Propiophenones, Benzil and Phenoxy derivatives and derivatives of Benzyl alcohol wen' examined for their arrhvthmia combating activity. Against acetylcholine induced auricular fibrillation U·0045 showed maximum activity and U -0172, U·OI77, U-OS75 and Lignocaine were more active than quinidine. In aconitine induced fibrillation li.OI77,...
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ژورنال
عنوان ژورنال: BJA Education
سال: 2020
ISSN: 2058-5349
DOI: 10.1016/j.bjae.2019.10.002